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62 - EL Schvartzapel - Junio 2010

  • Text
  • Schvartzapel
  • Entorno
  • Neuroplasticidad
  • Neurocognicion
  • Psico
  • Funciones
  • Bipolares
  • Trastorno
  • Diferentes
  • Memoria
  • Alteraciones
  • Cambios
  • Estudios
  • Bipolar
  • Pacientes
Alteraciones cognitivas en el trastorno bipolar: posibles etilogías

Dra. Edit

Dra. Edit Schvartzapel desencadenarán consecuencias diferentes debido a las diversas circunstancias neurobiológicas de estas etapas cronológicas. Los déficits cognitivos en el TBP serían pues, una manifestación emergente de la concurrencia y la combinación aleatoria de factores: iatrogénicos, alcoholismo y/o abuso de sustancias, cambios funcionales agudos asociados con depresión y/o manía, lesiones estructurales permanentes derivadas de procesos neurodegenerativos, lesiones estructurales permanentes originadas en el neurodesarrollo, cambios funcionales permanentes de origen genético y cambios funcionales permanentes causados por influencias del entorno. Referencias bibliográficas 1. Kupfer D J .The increasing medical burden in bipolar disorder, JAMA , 2005;(293):2528- 2530. 2. Isabella Soreca ,MD., Ellen Frank, PPh. D., D.J.Kupfer, M.D..The phenomenology of bipolar disorder: what drives the high rate of medical burden and determines long-term prognosis? Theoretical review. Depression and anxiety, 2009; (26):73-82. 3. Benedetti F, Serretti A, Colombo C, Barbini B,Lorenzi C, Campori E, Smeraldi E, influence of CLOCK gene polymorphism on circadian mood fluctuation and illness recurrence in bipolar depression, Am j Med Genet B Neuropsychiatr Genet 2003;( 123);23-26. 4. Martinez-Aran A,Vieta E, Reinares M, et al. Cognitive function across maniac or hipomaniac, depressed, and euthymic status in bipolar disorder, Am J Psychiatry 2004; (161): 262- 270. 5. Lupien JS, Mc Ewen BS, Gunnar MR, Heim C. Effects of stress throughout the lifespan on the brain, behavior and cognition, Nature 2009 (10); 434-445. 6. Weng G, Bhalla US, Iyengar R. Complexity in biological signaling systems, Science. 1999; (284): 92-96. 7. Manji HK, Chen G., Post-receptor signaling pathways in the pathophisiology and treatment of mood disorders, Curr. Psychiatry Rep. 2000; (2): 479-489. 8. Chen G, Rajkowska G, Du F, Seraji-Bozorgzad N, Manji HK., Enhancement of hippocampal neurogenesis by litium, J Neurochem2000; (75): 1729-34. 9. Farr G.H., Ferkey D M, Yost C, Pierce C B, Weaver C., Kimelman,D.,2000.Interaction among GSK3β,GBP,axin,and APC in Xenopus axis specification. J. Cell Biol, 2000; (148): 691-702. 0. Grimes CA, Jope R, The multifaceted roles of glycogen synthase kinase3β in cellular signaling. Progress in Neurobiology 2001 (65): 393- 400. 1. Lesort M., Stockmeier C., Jonson G. V. W.., Jope R. S. Journal of Neural Transmission, 1999; (106): 1217-1222. 2. Noga JT, Vladar K, Torrey EF. A volumetric magnetic resonance imaging study of monozygotic twins discordant for bipolar disorder. Psychiatry Res. 2001 Feb 28;106(1):25-34. 3. Lenox RH; Gould TD, Manji HK, Endophenotypes in bipolar disorder. Am J Med Genet. 2002; (114): 391-406. 4. Mattson MP, Mithocondrial regulation of neuronal plasticity. Neurochem Res 2007; ( 32): 707-715. 5. Williams JM, Thompson VL, Mason-Parker SE, Abraham WC; Tate WP, Synaptic activitydependent modulation of mitochondrial gene expression in the rat hippocampus. Brain Res Mol Res 1998; (60): 50-56. 6. Schloesser RJ, Huang J, Klein PS, Manji HK. Cellular plasticity cascades in the pathophysiology and treatment of bipolar disorder, Neuropsychopharmacology 2008; (33): 110- 133 7. Decina P, Kestenbaum CJ, Farber S, et al., Clinical and psychological assessment of children of bipolar probando, Am J Psychiatry. 1983; (140): 548-553. 8. Pierson A, Jouvent R, Quintín P, Perez-Diaz F, Leboyer M, Information processing déficits in relatives of manic depressive patients. Psychol Med 2000; (30): 545-555. 9. Ferrier IN, Chowdhury R, Thomson JM, Watson S, Young AH. Neurocognitive function in unaffected first-degree relatives of patients with bipolar disorder: a preliminary report. Bipolar Disorder 2004; (6): 319-323. 20. Gourovitch M L, Torrey EF, Gold J M, Randolph C, Weinberger DR, Goldberg T E, Neuropsychological performance of monozygotic twins discordant for bipolar disorder. Biol Psychiatry 1999; (45): 639-646. 21. Van Gorp WG, Altshuler L, Theberge DC, Wilkins J, Dixon W. Cognitive impairment in euthymic bipolar patients with and without prior alcohol dependence. Arch Gen Psychiatry. 1998; (55): 41-46. 22. Engelsmann F, Katz J, Ghadirian A M, Schachter D, Lithium and memory: a long term follow-up study, J Clin Psychofarmacol. 1988; (8): 207-211. 23. Manji HK, Moore GJ, Chen G, Clinical and preclinical evidence for the neurotrophic effects of mood stabilizers: implications for the pathophysiology and treatment of manic-depressive illness, Biol. Psychiatry 2000; (48): 740-754. 24. Blumberg HP, Stern E, Ricketts S et al., Rostral and orbital prefrontal cortex dysfunction in the manic states of bipolar disorder. Am J Psychiatry. 1999; (156): 1986-1988. 25. Davidson RJ, Pizzagalli D, Nitschke JB, Putnam K. Depression: perspectives from affective neuroscience .Ann Rev Psychol. 2002; (53): 545-574. 26. Op cit Blumberg HP, Leung HC, Skudlarski P. 27. Kessing LV. Cognitive impairment in the euthymic phase of affective disorder, Psychol Med. 1998; (28): 1027-1038. 28. Robinson LJ, Ferrier IN. Evolution of cognitive impairment in bipolar disorder: a systematic review of cross-sectional evidence, Bipolar disorder. 2006; (8): 103-116. 29. Verdoux H, Liraud F. Neuropsychological function in subjects with psychotic and affective disorders: Relationship to diagnostic category and duration of illness. Eur Psychiatry. 2000; (15): 236-243. 30. Strakowski SM, DelBello MP, Zimmerman ME et al., Ventricular and periventricular structural volume in first versus multiple episode bipolar disorder. Am J Psychiatry. 2002; (159): 1841-1847. 31. Kessing LV, Nilsson FM. Increased risk of developing dementia in patients with mayor affective disorders compared to patients with other medical illness. J Affect Disord. 2003; (73): 261-269. 32. Savitz J, Solms M, Remesar R, Neuropsychological dysfunction in bipolar affective disorder: a Critical opinion, Bipolar Disorder. 2005; (7): 216-235. 33. Nunes P, Florenza OV, Gattaz WF. Lithium and risk for Alzheimer disease in elderly patients with bipolar disorder, British Journal of Psychiatry. 2007; (190): 359-360. 34. Kestembaum CJ, Children at risk for manicdepressive illness: possible predictors. Am. J Psychiatry. 1979; (136): 1206-1208. 35. Savitz J, Solms M, Remesar R, Neuropsychological dysfunction in bipolar affective disorder: a critical opinion, Bipolar Disorder. 2005; (7):216-235. 36 // EDITORIAL SCIENS

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