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34 - EJ Zaidel - Junio de 2016

  • Text
  • Amiodarona
  • Pacientes
  • Efectos
  • Amiodarone
  • Arritmias
  • Ventricular
  • Bloqueo
  • Tratamiento
  • Dosis
  • Estudio
  • Cardio
Amiodarona desde el potencial de acción hasta los ensayos clínicos: ¿sigue vigente en el siglo XXI?

farmacología

farmacología cardiovascular 34 | Junio de 2016 Bibliografía sugerida • Rosenbaum MB, Chiale PA, Elizari MV, y col. Clinical efficacy of amiodarone as an antiarrhythmic agent. Am J Cardiol. 1976;38:934– 944. • The AFFIRM First Antiarrhythmic Drug Substudy Investigators. Maintenance of Sinus Rhythm in Patients With Atrial Fibrillation. J Am Coll Cardiol 2003;42:20-9. • Singh BN, Singh SN, Reda DJ, y col. Amiodarone versus Sotalol for Atrial Fibrillation. N Engl J Med 2005;352:1861-72. • Galperín J, Elizari MV, Chiale PA, y col. Efficacy of amiodarone for the termination of chronic atrial fibrillation and maintenance of normal sinus rhythm: a prospective, multicenter, randomized, controlled, double blind trial. J Cardiovasc Pharmacol Ther 2001;6:341-50. • Le Heuzey JY, De Ferrari G, Radzik D, y col. A Short-term, Randomized, Double-Blind, Parallel-group Study to Evaluate the Efficacy and Safety of Dronedarone versus Amiodarone in Patients with Persistent Atrial Fibrillation: The DIONYSOS Study. J Cardiovasc Electrophysiol. 2010;2:606-607. • Camm AJ, Capucci A,Hohnloser SH. A Randomized Active-Controlled Study Comparing the Efficacy and Safety of Vernakalant to Amiodarone in Recent-Onset Atrial Fibrillation. J Am Coll Cardiol 2011;57:313–21. • Kudenchuk PJ, Cobb LA, Copass MK, y col. Amiodarone for resuscitation after out-of-hospital cardiac arrest due to ventricular fibrillation. N Engl J Med 1999;341:871-8. • Dorian P, Cass D, Schwartz B, Cooper A, y col. Amiodarone as compared with lidocaine for shock-resistant ventricular fibrillation. N Engl J Med 2002;21:884-90. • The Antiarrhythmics Versus Implantable Defibrillators (AVID) Investigators. A comparison of antiarrhythmic-drug therapy with implantable defibrillators in patients resuscitated from near-fatal ventricular arrhythmias. N Engl J Med. 1997;337:1576–1583. • Sheldon RS, Roberts R, Mitchell LB, Wyse G, Duff HJ, Gillis AM, Connolly SJ. Selection of VT/VF patients most likely to benefit from ICD compared to amiodarone therapy in the Canadian Implantable Defibrillator Study. Circulation. 1998;98:I-495. • Pratt CM, Greene HL, Anderson JL, Cobb LA, Ehiert F, Epstein AE, Flynn D, Kim S, Richardson DW, Schron E, Moore R, for The Antiarrhythmics vs ICD Investigators. Circulation. 1998;9:I-49–I-50. • Elizari, M, Martinez, JM, Belziti, C y col. Mortality following early administration of amiodarone in acute myocardial infarction: results of the GEMICA trial. Circulation. 1996; 94: 90. • Ceremuzynski, L, Kleczar, E, Krzeminska- Pakula, M y col. Effect of amiodarone on mortality after myocardial infarction: a doubleblind, placebo-controlled, pilot study. J Am Coll Cardiol. 1992; 20: 1056–1062. • Navarro-Lopez, F, Cosin, J, Bayes de Luna, A, and the SSSD Investigators. Comparison of the effects of amiodarone versus metoprolol on the frequency of ventricular arrhythmias and on mortality after acute myocardial infarction. Am J Cardiol. 1993; 72:1243–1248. • Deedwania PC, Singh BN, Ellenbogen K, y col. Spontaneous conversion and maintenance of sinus rhythm by amiodarone in patients with heart failure and atrial fibrillation: observations from the Veterans Affairs congestive heart failure survival trial of antiarrhythmic therapy (CHF-STAT). Circulation. 1998;98:2574-9. • Burkart, F, Pfisterer, M, Kiowski, W, y col. Effect of antiarrhythmic therapy on mortality in survivors of myocardial infarction with asymptomatic complex ventricular arrhythmias: Basel Antiarrhythmic Study of Infarct Survival (BASIS). J Am Coll Cardiol. 1990;16:1711– 1718. • Cairns JA, Connolly SJ, Roberts RS, y col. Randomised trial of outcome after myocardial infarction in patients with frequent or repetitive ventricular premature depolarisations: CAMIAT. Lancet. 1997;349:675–682 • Julian DG, Camm AJ, Frangin G, y col. Randomised trial of effect of amiodarone on mortality in patients with left ventricular dysfunction after recent myocardial infarction: EMIAT. Lancet. 1997;349:667–674. • Singh, SN, Fletcher, RD, Fisher, SG, y col. Survival Trial in Congestive Heart Failure.Amiodarone in patients with congestive heart failure and asymptomatic ventricular arrhythmia. N Engl J Med. 1995;333:77–82. • Doval, HC, Nul, DR, Grancelli, HO, Perrone, SV, Bortman, GR, Curiel, R, and for Grupo de Estudio de la Sobrevida en la Insuficiencia Cardiaca en Argentina (GESICA). Randomised trial of low-dose amiodarone in severe congestive heart failure. Lancet. 1994;344:493–498. • Garguichevich, JJ, Ramos, JL, Gambarte, A, y col. Effect of amiodarone therapy on mortality in patients with left ventricular dysfunction and asymptomatic complex ventricular arrhythmias: Argentine pilot study of sudden death and amiodarone (EPAMSA). Am Heart J. 1995;130:494–500. • Amiodarone Trials Meta-Analysis Investigators. Effect of prophylactic amiodarone on mortality after acute myocardial infarction and in congestive heart failure: meta-analysis of individual data from 6500 patients in randomised trials. Lancet. 1997;350:1417–24. • CASCADE Investigators. The CASCADE Study: randomized antiarrhythmic drug therapy in survivors of cardiac arrest in Seattle. Am J Cardiol. 1993;26:70F-74F. • Connolly SJ, Dorian p, Roberts RS, y col. Comparison of β-Blockers, Amiodarone Plus β- Blockers, or Sotalol for Prevention of Shocks From Implantable Cardioverter DefibrillatorsThe OPTIC Study: A Randomized Trial. J Am Med Asoc 2006;295:165-171. Editorial Sciens | 9

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